1,3-Dihydroxyacetone Mekhoa ea Tlhahiso le Likopo kenyelletso CAS 96-26-4

1,3-Dihydroxyacetone Kenyelletso

1,3-Dihydroxyacetone ke motsoako oa motsoako o nang le motsoako oa molek'hule C3H6O3, e leng polyhydroxyketose le ketose e bonolo ka ho fetisisa.Ponahalo ke kristale e tšoeu ea phofo, e qhibilihang habonolo linthong tse hlapollang tse kang metsi, ethanol, ether le acetone.Sebaka se qhibilihang ke 75-80 ℃, 'me ho qhibiliha ha metsi ke> 250g/L (20 ℃).E na le tatso e monate mme e tsitsitse ho pH 6.0.1,3-Dihydroxyacetone ke tsoekere e fokotsang.Li-monosaccharides tsohle (ha feela ho na le lihlopha tsa mahala tsa aldehyde kapa ketone carbonyl) li na le ho fokotseha.Dihydroxyacetone e kopana le maemo a kaholimo, ka hona ke ea sehlopha sa ho fokotsa tsoekere.

Ho na le haholo-holo mekhoa ea ho kopanya lik'hemik'hale le mekhoa ea ho belisoa ha likokoana-hloko.Ho na le mekhoa e meraro ea mantlha ea lik'hemik'hale bakeng sa 1,3-dihydroxyacetone: electrocatalysis, metal catalytic oxidation, le formaldehyde condensation.Tlhahiso ea lik'hemik'hale ea 1,3-dihydroxyacetone e ntse e le sethaleng sa lipatlisiso tsa laboratori.Tlhahiso ea 1,3-dihydroxyacetone ka mokhoa oa likokoana-hloko e na le melemo e mengata: lihlahisoa tse phahameng tsa lihlahisoa, tekanyo e phahameng ea phetoho ea glycerol le theko e tlaase ea tlhahiso.Tlhahiso ea 1,3-dihydroxyacetone Chaena le linaheng tse ling haholo-holo e amohela mokhoa oa ho fetola likokoana-hloko tsa glycerol.

Mokhoa oa ho kopanya lik'hemik'hale

1. 1,3-dihydroxyacetone e entsoe ho tloha 1,3-dichloroacetone le ethylene glycol e le lisebelisoa tse ka sehloohong tse tala ka tšireletso ea carbonyl, etherification, hydrogenolysis, le hydrolysis.1,3-dichloroacetone le ethylene glycol li futhumatsoa 'me li kenngoa hape ka toluene ho hlahisa 2,2-dichloromethyl-1,3-dioxolane.Joale ba itšoara ka sodium benzylidene ho N, N-dimethylformamide ho hlahisa 2,2-dibenzyloxy-1,3-dioxolane, eo ka nako eo e leng hydrogenated tlas'a Pd / C catalysis ho etsa synthesize 1,3-dioxolane-2,2-dimethanol, e leng ebe e kenngoa ka hydrolyzed ka hydrochloric acid ho hlahisa 1,3-dihydroxyacetone.Thepa e tala bakeng sa synthesizing 1,3-dihydroxyacetone ho sebelisa mokhoa ona ho bonolo ho e fumana, maemo a karabelo a bonolo, 'me Pd / C catalyst e ka tsosolosoa, e nang le bohlokoa ba kopo ea bohlokoa.

2. 1,3-dihydroxyacetone e entsoe ho tloha 1,3-dichloroacetone le methanol ka tšireletso ea carbonyl, etherification, hydrolysis, le hydrolysis reactions.1,3-dichloroacetone e sebetsana le methanol e feteletseng ea anhydrous ka pel'a mokelikeli ho hlahisa 2,2-dimethoxy-1,3-dichloropropane, e ntan'o futhumatsoa ka sodium benzylate ho N, N-dimethylformamide ho hlahisa 2,2-dimethoxy. -1,3-dibenzyloxypropane.E ntan'o ba hydrogenated tlas'a Pd / C catalysis ho hlahisa 2,2-dimethoxy-1,3-propanediol, eo ka nako eo e leng hydrolyzed ka hydrochloric acid ho hlahisa 1,3-dihydroxyacetone.Tsela ena e nka sebaka sa mosireletsi oa carbonyl ho tloha ethylene glycol ho methanol, ho etsa hore ho be bonolo ho arola le ho hloekisa sehlahisoa sa 1,3-dihydroxyacetone, se nang le tsoelo-pele ea bohlokoa le boleng ba tšebeliso.

3. Synthesis ea 1,3-dihydroxyacetone e sebelisang acetone, methanol, chlorine kapa bromine e le lisebelisoa tse ka sehloohong tse tala.Acetone, anhydrous methanol, le chlorine gas kapa bromine li sebelisoa ho hlahisa 2,2-dimethoxy-1,3-dichloropropane kapa 1,3-dibromo-2,2-dimethoxypropane ka mokhoa oa pitsa e le 'ngoe.Joale li etherified ka sodium benzylate ho hlahisa 2,2-dimethoxy-1,3-dibenzyloxypropane, eo ka nako eo e leng hydrogenated le hydrolyzed ho hlahisa 1,3-dihydroxyacetone.Tsela ena e na le maemo a bonolo, 'me "pitsa e le' ngoe" e qoba tšebeliso ea 1,3-dichloroacetone e theko e boima, e etsang hore e be theko e tlaase le ea bohlokoa haholo bakeng sa nts'etsopele.

Lisebelisoa

1,3-Dihydroxyacetone ke ketose ea tlhaho e ka senyehang, e jeoang, ebile e se chefo 'meleng oa motho le tikolohong.Ke tlatsetso e nang le mesebetsi e mengata e ka sebelisoang indastering ea litlolo, ea meriana le ea lijo.

E sebelisoa indastering ea litlolo

1,3-Dihydroxyacetone e sebelisoa haholo-holo e le motsoako oa motsoako oa litlolo, haholo-holo e le setlolo se sireletsang letsatsi se nang le liphello tse khethehileng, se ka thibelang ho tsoa ho feteletseng ha mongobo oa letlalo, 'me se phetha karolo ea ho kolobisa, ho sireletsa letsatsi, le tšireletso ea mahlaseli a UV.Ho phaella moo, lihlopha tse sebetsang tsa ketone ho DHA li ka itšoara ka li-amino acid le lihlopha tsa amino tsa keratin ea letlalo ho etsa polymer e sootho, e leng se etsang hore letlalo la batho le hlahise 'mala o sootho oa maiketsetso.Ka hona, e ka boela ea sebelisoa e le mohlala oa ho pepeseha ha letsatsi ho fumana letlalo le sootho kapa le sootho le shebahalang le tšoana le phello ea nako e telele ea mahlaseli a letsatsi, ho etsa hore e shebahale e le ntle.

Ntlafatsa peresente ea nama ea kolobe

1,3-Dihydroxyacetone ke sehlahisoa sa mahareng sa metabolism ea tsoekere, se bapala karolo ea bohlokoa ts'ebetsong ea metabolism ea tsoekere, ho fokotsa mafura a 'mele oa kolobe le ho ntlafatsa peresente ea nama e mafura.Basebeletsi ba Majapane ba saense le thekenoloji ba bontšitse ka liteko hore ho eketsa palo e itseng ea DHA le motsoako oa pyruvate (calcium letsoai) lijong tsa kolobe (ka tekanyo ea boima ba 3: 1) ho ka fokotsa mafura a nama ea kolobe ka 12% ho 15%, 'me mafura a nama ea leoto le mesifa e telele ka ho fetisisa ea mokokotlo le tsona li fokotsehile, ka keketseho ea protheine.

Bakeng sa lijo tse sebetsang hantle

Ho tlatselletsa 1,3-dihydroxyacetone (haholo-holo hammoho le pyruvate) ho ka ntlafatsa sekhahla sa metabolism ea 'mele le mafura a acid oxidation, ho ka chesa mafura a' mele ho fokotsa mafura a 'mele le ho liehisa ho fumana boima ba' mele (tahlehelo ea boima ba 'mele), le ho fokotsa sekhahla sa ts'oaetso. mafu a amanang.E ka boela ea ntlafatsa kutloisiso ea insulin le ho fokotsa boemo ba k'holeseterole ea plasma e bakoang ke lijo tse phahameng tsa k'holeseterole.Tlatsetso ea nako e telele e ka eketsa lebelo la ts'ebeliso ea tsoekere ea mali le ho boloka mesifa ea glycogen, Bakeng sa baatlelete, e ka ntlafatsa ts'ebetso ea bona ea mamello ea aerobic.

Lisebelisoa tse ling

1,3-dihydroxyacetone e ka boela ea sebelisoa ka ho toba e le reagent ea antiviral.Mohlala, moetlong oa lesea la mahe a likhoho, ts'ebeliso ea DHA e ka thibela haholo ts'oaetso ea kokoana-hloko ea distemper, e bolaeang 51% ho isa ho 100% ea kokoana-hloko.Ka indasteri ea letlalo, DHA e ka sebelisoa e le moemeli oa tšireletso bakeng sa lihlahisoa tsa letlalo.Ho feta moo, li-preservatives tse entsoeng haholo ka DHA li ka sebelisoa bakeng sa ho boloka le ho boloka litholoana le meroho, lihlahisoa tsa metsing le lihlahisoa tsa nama.