Tokisetso ea procaine & procaine hcl

Motheo oa procaine

CAS: 59-46-1

Ponahalo: phofo e tšoeu ea kristale

Sebaka se qhibilihang (sebaka se belang): 59 ~ 62 ℃

Foromo ea molek'hule: c13h2on2o2

Boima ba molek'hule: 236.31

Procaine hcl

CAS: 51-05-8

Ka botlolong ea 250ml e meraro ea melamo e nang le sehlahisoa le thermometer, tharollo ea nitrocaine e nang le pH ea 4.0-4.2 e ea kenngoa.Tlas'a ts'usumetso e felletseng, phofo ea tšepe e kentsoeng e eketsoa ho 25 ℃ ka makhetlo a 'maloa.Kamora ho eketsa, mocheso oa karabelo o nyoloha ka bohona mme o boloka 40-45 ℃.Nako ea karabelo e ne e le lihora tse 2.Kamora ho hloekisoa, masala a filthara a hlatsuoa habeli ka metsi a manyane, tharollo ea ho hlatsoa e kopantsoe le filtrate, acidified ho pH 5 ka dilute hydrochloric acid (10%), 'me tharollo e tletseng sodium sulfide e eketsoa ho pH 7.8- 8.0 ho fokotsa letsoai la tšepe ka tharollo ea karabelo.Filtrate e acidified ho ph6 ka palo e nyane ea dilute hydrochloric acid, ebe e futhumatsoa ka 50-60 ℃ metsotso e 10 ka khabone e nyane e kentsoeng.Masala a sefahla a hlatsuoa hanngoe ka metsi a seng makae, tharollo ea ho hlatsoa e kopantsoe le filtrate, e pholile ho ea ka tlase ho 10 ℃, 'me alkalized le 20% NaOH ho fihlela procaine e arohane ka ho feletseng (pH 9.5-10.5).Sefa, hlatsoa habeli, tobetsa 'me u ntše metsi bakeng sa ho etsa letsoai(procaine hcl)