Sehlahisoa: 2-phenylacetamide
Foromo ea molek'hule: C8H9NO
Boima ba molek'hule: 135.17
Lebitso la Senyesemane: Phenylacetamide
Sebopeho: Letlapa le lesoeu kapa likristale tse bōpehileng joaloka lekhasi.Mp 157-158 ℃, bp 280-290 ℃ (ho bola).E qhibiliha ka metsing a chesang le ethanol, e qhibiliha hanyenyane metsing a batang, ether le benzene.
Tšebeliso: Bohareng ba lithethefatsi tse kang penicillin le phenobarbital.E boetse e sebelisoa bakeng sa ho lokisa phenylacetic acid, linoko le chefo e bolaeang likokoanyana.
Mokhoa oa 1) Masoko F，Katsura T.US 4536599A1.1985.
Eketsa 117.2 g (1.0 mol) ea phenylacetonitrile (2), 56.1 g ea 25% potassium hydroxide tharollo, 291.5 g ya 35% hydrogen peroxide aqueous tharollo, 1.78 g ea benzyltriethylammonium chloride, le 351.5 g ho itsoara joang ka isopropano.Hlohlelletsa 'me u arabe ka 50 ℃ bakeng sa lihora tse 4.Ka mor'a hore karabelo e phethoe, isopropanol e fetoha mouoane tlas'a khatello e fokotsehileng, e pholile, e tlhotliloeng, e hlatsuoa ka metsi, 'me e omisitsoe ho fumana motsoako (1) 128.5 g, mp 155 ℃, ka lihlahisoa tsa 95%.
Mokhoa oa 2) Furniss BS, Hannaford AJ, Rogers V, le al.Buka ea Vogel's Textbook of Practical Chemistry.Longman London le New York.Khatiso ea bone,1978:518.
Kenya 100 g (0.85 mol) ea phenylacetonitrile (2) le 400 mL ea concentrated hydrochloric acid ho flask ea reaction.Ha u ntse u hlohlelletsa, itšoara ka 40 ℃ metsotso e ka bang 40, 'me u phahamisetse mocheso ho 50 ℃.Tsoela pele ho itšoara ka metsotso e 30.Pholisa ho 15 ℃ 'me u kenye 400 mL ea metsi a batang a pholileng ka tsela e theohang.Ho pholile ka bateng ea metsi a leqhoa, ho hloekisa likristale.Eketsa se tiileng ho 50 ml ea metsi 'me u hlohlelletse hantle ho tlosa phenylacetic acid.Sefa le ho omisa ho 50-80 ℃ ho fumana 95 g ya phenylacetamide (1), mp 154-155 ℃, ka lihlahisoa tsa 82%.Recrystallization ka ethanol, mp 156 ℃.
Nako ea poso: Apr-11-2023